Saturday, April 27, 2019

Cancer Prevention Primary Prevention

(Primary Prevention)

So here we have a critically important topic, critically important for several reasons. There is an epidemic of cancer; we believe that the majority of these cases are preventable, and we know a good deal about etiology, the cause and prevention of cancer. A huge, burgeoning industry has built up around treating cancer; at the same time, the focus on prevention and the resources dedicated to the prevention of cancer is growing a bit, but grossly inadequate. Will the disease of cancer soon take the place of heart disease as the number one killer in our country?

Yes, more than 40 years has elapsed since the war on cancer was officially declared by Pres. Nixon. And, we are no closer to winning that war than we were when it was declared!

This topic is not only legitimate, complex, and important, but it is part of a bigger picture, the whole issue of the epidemic of chronic diseases in general. As a culture and within the health care system in general we are struggling with a full spectrum of chronic diseases including dementia and other brain diseases including stroke, heart disease, cancer, autoimmune disorders, diabetes and prediabetes, obesity, addictions, and a rising incidence of suicide. A pivotal issue in this discussion has to do with the idea of synergy and a growing body of knowledge indicating that many if not most of these chronic medical conditions have common causation. So, if I consume a plant strong eating regimen, it is likely that my risk for these diseases will decrease dramatically. The environmental factors and dietary issues that help prevent cancer also act to prevent many of the other chronic diseases.



Yes, it is also true is that statistically, most people do not get cancer; however, the majority of people do contract one or more chronic diseases that make up the total disease burden in our country and in the western world. In the primary prevention of disease our goal is to avoid contracting serious illness for a lifetime and, that would include the disease of cancer. But, I must add that adherence to even ideal lifestyle practices is not a guarantee of optimal health or extended longevity; this is because there remains a series of issues that are outside of our control:

·       There are many toxic environmental exposures over which we have little or control.

·       Having a sunburn at age 15 may result in a skin cancer at age 50.

·       Certain cancers like breast, uterine, ovarian and prostate can be triggered in part by the food our mothers ate and the chemicals in their environments.

·       Despite an ideal food intake and a dedicated exercise regimen, they cannot insulate us from dangerous working conditions that may perhaps include exposure to asbestos or other high-risk situations.

·       And finally, it is also true that our understanding of lifestyle factors is evolving; and, this understanding is therefore not perfect. In our culture in past decades we used to strongly advocate the consumption of dairy products, but now we understand the role that dairy products play in the onset of cancer, in part, because of increased levels of insulin growth factor one (IGF-1).



It is instructive to note that several specific people groups discussed below appear not to contract cancer at all, or have a remarkably low incidence of cancer



Blue Zones

The five Blue Zone people groups have been spared this troublesome disease. A Blue Zone is a geographic area where there has been exceptional longevity and an extraordinary low incidence of most all disease, including cancer.  Some of these people may live to be centenarians or even super centenarians (100-110 years or longer).

·       The Okinawans: This is home to the world’s healthiest documented elders, to the world’s longest recorded life expectancies, and to the highest concentration of verified centenarians in the world! Okinawan elders have incredibly young arteries, lower risk for heart disease and stroke, low risk for hormone dependent cancers, strong bones, sharp minds, slim bodies, natural menopause, healthy levels of sex hormones, and excellent psycho-spiritual health. They eat squash, papayas, greens, tomatoes, leaks, melons containing cancer fighting antioxidants, sea vegetables, and soy that is mostly from relatively unprocessed soy products like tofu, edamame, miso, soy flour, and soy milk. They avoid eating junk food that creates inflammation. Compared to someone in the United States, an elderly Okinawan is 85% less likely to die from breast cancer, 88% less likely to die from prostate cancer, 70% less likely to die from ovarian cancer, and 70% less likely to die from colon cancer.

·       The Seventh-day Adventists: As a group, they currently lead the nation in longest life expectancy. Over 9,000 Seventh-day Adventists live in and around Loma Linda, California, 60 miles east of Los Angeles. There are approximately 24 million Adventist adherents worldwide and about 1 million Adventists in the United States and Canada combined. This blue zone group has been the focus of exhaustive, multi-decade long research concerning their health and longevity. Some of their cultural characteristics include:

1.) They find a sanctuary in time; their 24-hour Sabbath allows time to focus on family, God, nature, time to relieve stress, and participate in social activities.

2.) They seek to maintain a healthy body mass index (BMI), to keep active, and, if they consume meat, do it sparingly. They have lower blood pressure, lower blood cholesterol and less cardiovascular disease than heavier Americans with higher BMIs. To reduce the odds of having heart disease and certain cancers they get regular moderate exercise like low intensity daily walking.

3.) Tendency wise, Adventists tend to spend lots of time with other Adventists. They find well-being in this by sharing values and supporting each other’s habits.



4.) They snack on nuts and find that those who consume nuts at least five times a week have about half the risk of heart disease and live about two years longer than those who do not.



5.) These people focus on helping others and volunteering as a way to find a sense of purpose and to give something back to their church and community.



6.)  Many Adventists adhere to a vegetarian diet as consuming fruits, vegetables and whole grains appears to be protective against a wide variety of cancers. For those who do consume meat they recommend eating small portions as a side dish rather than as a main part of the meal.





7.) The Adventist tendency is to eat an early, lite dinner that avoids flooding the body with calories during the inactive parts of the day; this seems to promote better sleep and a lower BMI.



8.) Non-smoking Adventists who ate fruit daily, consumed legumes three times a week, and consumed tomatoes three or four times weekly, had significant health benefits including reduction in cancers.





9.) Finally, the Adventists drink plenty of water every day, 5 to 6 glasses and believe that this resulted in a substantial reduction in the risk of fatal heart attacks.

·       Sardinians: For the most part it would never occur to these people to be bored; they love their life, their animals, their farming and their families. Their families are their purpose in life, la famiglia is considered the most important thing in their lives. Their diet consists of mastic oil that has antibacterial and antimutagenic properties, barley, fava beans, chickpeas, tomatoes, almonds, sheep’s milk, milk thistle tea, cheese, potatoes, onions, zucchini, onions, and Sardinian wine that is a potent source of flavonoid nutrients that may protect against cancer and heart disease.



·         Costa Rica, Nicoya Peninsula: These centenarians on the Nicoya Peninsula in Costa Rica have some important lessons to share with us about longevity and disease prevention that warrant them having the distinguished status of being a Blue Zone people. These folks have a physically active lifestyle, an excellent diet, and, importantly, they have succeeded in achieving lifelong happiness; this very positive ingrained mood state, happiness, can add a decade to a person’s health span. Their food consumption includes exotic fruits, lime-soaked corn tortillas, bananas, papayas, beans, onions, garlic, fresh tomatoes, jalapeno peppers, corn, cilantro and cheese. In many instances, their tap water has very high levels of healthy calcium and magnesium.

·       Ikaria, Greece: On average, these people live an astounding 8 to 10 years longer than Americans and they are included in the elite blue zone category. They consume a diverse Mediterranean diet that includes vegetables, legumes, greens, olive oil and olives, hummus, tea from local herbs, goat’s milk, potatoes, coffee, wine in moderation, local honey and fish. They consume no processed food and little or no sugar. Beans and pulses are clearly one of the most important aspects of traditional Ikarian eating; fava or broad beans, chickpeas, black-eyed peas and lentils are core food items. Each of these legumes are packed with fiber, minerals, cholesterol free protein, antioxidants and other phytochemicals, and vitamins such as folate.



Cold Spots

Cold Spots are places where we find very few cases of a specific disease like heart disease, cancer, osteoporosis or diabetes. But, these groups do have other illnesses.

·       Cameroon, West Africa: These people had superior bowel health and avoided colon cancer. They soak their Manioc (cassava or yucca) to remove toxic residues. This clearly contributes to their bowel health by minimizing exposure to harmful toxins. They consume a minimum of 35 grams of fiber daily from foods such as fruits, vegetables, beans, nuts, and whole grains. Secondly, they consume foraged greens such as collard greens, mustard greens, dandelion greens and spinach that are rich in folate and many other phytonutrients. Thirdly, they consume African grains such as millet, sorghum, and teff and soak these grains overnight in order to increase the bioavailability of the nutrients. Finally, their people do some form of aerobic exercise for at least 30 minutes six days a week.

·       Hispanics: They have less cancer of the prostate, breast, and colon that is associated with consumption of all sorts of legumes; and, also consume a good deal of corn, tomatoes, chili peppers, rice and corn.

·       Papua New Guinea Highlanders and Kitavans: This is a cold spot for dementia, cancer and stroke. Refined sugar, vegetable oils and other processed foods were virtually nonexistent; primarily they eat a variety of tubers including yams, sweet potatoes, taro and cassava.

·       Tarahumara Indians: This group has an extremely low incidence of heart disease and cancer. They are probably the most efficient and fastest runners in the world! There diet it is primarily complex carbohydrates like beans, corn and squash.



Other Long-live Groups

** Note that the elderly in each of these three groups have extremely low rates of cancer and all of the other major chronic diseases.


·       The Abkhasians: The Abkhasian people reside in the Caucasus Mountains in southern Russia. Their land is bordered on the north by Russia and on the south by Georgia. Abkhasia covers 3,000 square miles between the eastern shores of the Black Sea and the crest line of the main Caucasus Mountain range. Many of these people are thought to live to be over 100 years of age and several of them are believed to be over 130 years old. They hike up and down steep hillsides and they actively work in the orchards and gardens. They have a relentless sense of humor and dislike being rushed. They tend to be lacto-vegetarians who rarely eat meat. They consume a fermented beverage called Matzoni that is made from the milk of goats, cows or sheep. For breakfast they often have freshly picked vegetables; at all three meals they eat their beloved Abista that is a cornmeal porridge. They do not consume leftover foods; if the food is not totally fresh they consider it harmful and they discard it. The average total cholesterol reading among the Abkhasian centenarians is 98!

·       The Hunzans: The Hunza people are also known as the Burusho, and inhabit the Hunza Valley in the Gilgit-Baltistan region of northernmost Pakistan, where Pakistan meets Russia and China. These people live in an area where mountain peaks soar to 20,000 feet and where they live in a very fertile valley that has sustained the population of 10 to 30,000 people for 2,000 years. There are no overweight people. It is thought that some of the men can father children at 100 years of age. Their fertile planting terraces have been called one of the great wonders of the world. They grow many varieties of fruit and have a multitude of wild berries. Their food supply includes more than 20 varieties of apricots and the roof of every building is covered with drying apricots. They consume a lot of whole-grains including wheat, barley, millet, and buckwheat and they eat the seeds of a grass called ‘Job’s Tears.’ Much of their diet is consumed raw, including corn on the cob. They do not overcook their vegetables which are often lightly steamed in order to save water and preserve nutrients. Interestingly, they consume highly nutritious ground flaxseed frequently. Their apples are very large, weighing more than a pound each! The percent of their calories from carbohydrates is about 73%, from fat is about 17%, and from protein is about 10%.  They have a shortage of fuel so they eat much of their food raw. Their air, water, and soil is very healthy and this would appear to be a major contribution to their longevity and health status. They tend to be a happy and passionate people who work in the fields until their most senior years.

·       The Vilcabambans: This people group lives in a very small and inaccessible town in southern Ecuador’s Andes Mountains called Vilcabamba which means Sacred Valley. This area is not far from the Peruvian border and is about 100 miles inland from the Pacific Ocean. Their land is lush and in a subtropical region. Some people have described their area as the Lost Paradise, because of the area’s serenity, clean air, wonderful blue sky and pure drinking water. They are quite lean, have a very healthy diet, low cholesterol levels, and they are very physically active. The Vilcabambans are known to live for a very long time, many of them being centenarians.  They are almost entirely vegetarian consuming a lot of whole grains, vegetables, fruit, seeds, beans, and nuts. It is a rare occasion when they consume milk, eggs, meat or butter. Their protein comes from vegetables, whole grains and a variety of beans. Their fat comes from avocados, seeds and nuts. Their carbohydrates include whole grain cereals such as corn, quinoa, wheat, and barley; they also consume tubers in the form of white potatoes, yucca and sweet potatoes. Regular exercise is an integral part of their culture and a very important part of their daily lives. They know the value and healing power of walking great distances and they have a famous saying: ‘Each of us has two doctors, the left leg and the right leg.’ They often negotiate very hilly terrain, perhaps even daily, and as a result, they have a high degree of cardiovascular fitness. And again, they have extremely low rates of cancer and other chronic diseases.

Summary of Some Select Dietary and Lifestyle Issues in Indigenous Populations

As we study the characteristics of healthy indigenous cultures to include their dietary habits, their relationships, and the level of their physical activity, we see a picture of lifestyles that lead to optimal health, including the avoidance of cancer. Here are some of those characteristics:

  • When possible, eat foods that are local, fresh, and in season. Avoid canned goods and foods that have been shipped long distances.
  • Follow through with food cultivation techniques and recipes that are passed down through the generations.
  • Practice communal eating, eat for satiety rather than fullness, and fast periodically.
  • Use sugar that comes from whole plant foods such as honey, fruits, vegetables and whole grains.
  • Use salt that comes from natural unprocessed sources such as fish, sea greens and vegetables.

  • Consume meat in very small quantities and get your protein mainly from plant sources such as nuts, legumes and grains. Consume fish sparingly. As these people transition from small amounts of animal-based foods to significant amounts, we see more heart disease and cancer.
  • Consume non-meat dietary fats from whole nuts, seeds, grains and fatty fruits. Some fish also contain healthy fat. Avoid bottled oils, margarine, saturated animal fats and cholesterol.
  • Eat fermented and pickled foods.
  • Consume a diverse selection of healing spices like turmeric and ginger that have anti-inflammatory properties.
  • Eat a plant-based diet that is low in overall calories and high in nutrients.
  • Eat a diet high in complex carbohydrates including plenty of whole grains, vegetables and fruits.
  • Consume whole plant foods and eat very little if any processed or refined foods, sugar, corn syrup, preservatives, artificial flavors or other chemicals. Consume at least 75% of your calories from unrefined plant-based foods.
  • Consume plenty of high starch plant foods including corn, beans, potatoes and squash.
  • Eat an assortment of small dishes in order to optimize variety in the diet. In Crete these are called mezes; in Okinawa they are Okazu; and in Spain they are tapas.

  • Light alcohol consumption.
  • Eat slowly.
  • Get sufficient sleep and rest; many take naps, some regularly, a practice that reduces stress and may lower the risk for heart disease.
  • Nurture all of your relationships within your family, circle of friends, neighbors, community, and place of worship. Maintain a strong sense of belonging to your community and strong ties with your friends.

  • Engage in daily activities that relieve stress including daily, regular exercise.
  • Fast when you feel poorly.
  • Minimize exposure to toxins in the air, water, and food; minimize use of medications when possible.
  • Remain sexually active into your latest years.
  • Be active in faith-based activities.
  • Maintain a strong sense of purpose in life. (Zahler, 2018)

References

Buettner, Dan: ‘Blue Zones,: lessons for living longer from the people who’ve lived the longest,’ National Geographic Society, 2008.

Campbell, T.C.: ‘Whole, Rethinking the Science of Nutrition,’ Ben Bella Books, 2013.

Popper, Pamela: ‘Solving America’s health care crisis,’ PB Industries, Inc., 2012.

Robbins, John: ‘Healthy At 100,’ Ballantine Books, 2006.

Zahler, William: ‘Health, Inertia, and Information: Why Are We Sick?’ Create Space, March 2018.

Zahler, William: ‘Synergy and the Dynamics of Lifestyle Change,’ Create Space, January 2019.



William Zahler, MSW, ACLM

April, 27, 2019





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